Generation of a human induced pluripotent stem cell line from a familial Alzheimer's disease PSEN1 T119I patient
نویسندگان
چکیده
Human induced pluripotent stem cells (hiPSC) line FLENIi001-A was reprogrammed from dermal fibroblasts using the lentiviral-hSTEMCCA-loxP vector. Fibroblasts were obtained a skin biopsy of 72-year-old Caucasian male familial Alzheimer's disease patient carrying T119I mutation in PSEN1 gene. genotype maintained and stemness pluripotency confirmed hiPSC line.
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ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2021
ISSN: ['1876-7753', '1873-5061']
DOI: https://doi.org/10.1016/j.scr.2021.102325